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Synthesis of 4-substituted glutarimides by free...
Journal article

Synthesis of 4-substituted glutarimides by free radical addition of iodoacetamide to α,β-unsaturated esters

Abstract

Free radical addition of either methyl bromoacetate or iodoacetamide to an α,β,-unsaturated ester gave the 4-substituted glutarate or glutarimide respectively, whereas the radical cyclisation of N-bromoacetyl crotonamide gave the 2-substituted succinimide.

Authors

Sacripante G; Tan C; Just G

Journal

Tetrahedron Letters, Vol. 26, No. 46, pp. 5643–5646

Publisher

Elsevier

Publication Date

January 1985

DOI

10.1016/s0040-4039(01)80908-4

ISSN

0040-4039