Journal article
Oxytocin Pretreatment Decreases Oxytocin-induced Myometrial Contractions in Pregnant Rats in a Concentration-dependent But Not Time-dependent Manner
Abstract
Recent biomolecular studies have shown that continuous exposure of human myometrial cells to oxytocin results in a significant loss of responsiveness to subsequent oxytocin stimulation, perhaps because of desen-sitization of the oxytocin receptors. However, it is unclear whether this phenomenon results in a reduction of the contractile activity of the uterine muscle in humans or animals. The objective of our study was to investigate the in …
Authors
Magalhaes JKRS; Carvalho JCA; Parkes RK; Kingdom J; Li Y; Balki M
Journal
Reproductive Sciences, Vol. 16, No. 5, pp. 501–508
Publisher
Springer Nature
Publication Date
May 2009
DOI
10.1177/1933719108329954
ISSN
1933-7191