Journal article
Effects of Dose Rate on the Reproductive Cell Death and Early Mitochondrial Membrane Potential in Different Human Epithelium-Derived Cells Exposed to Gamma Rays
Abstract
Dose rate is one of the most varied experimental parameters in radiation biology research. In this study, effects of dose rates on the radiation responses of 2 different types of human epithelium-derived cells, immortalized keratinocytes (HaCaT), and colorectal cancer cells (HCT116 p53+/+ and HCT116 p53-/-) were systematically studied. Cells were γ-irradiated at one of the 4 dose rates (24.6, 109, 564, and 1168 mGy/min) to a total dose of 0.5 …
Authors
Vo NTK; Shahid M; Seymour CB; Mothersill CE
Journal
Dose-Response, Vol. 17, No. 2,
Publisher
SAGE Publications
Publication Date
April 1, 2019
DOI
10.1177/1559325819852508
ISSN
1540-1421