Journal article
Comparison of the source and prognostic utility of cfDNA in trauma and sepsis
Abstract
BackgroundCirculating cell-free DNA (cfDNA) may contribute to the pathophysiology of post-injury inflammation and coagulation in trauma. However, the source and mechanism of release of cfDNA in trauma is not well understood. One potential source of cfDNA is from Neutrophil Extracellular Traps (NETs), released by activated neutrophils during the process of NETosis. The primary objective of our study was to determine if cfDNA has prognostic …
Authors
Jackson Chornenki NL; Coke R; Kwong AC; Dwivedi DJ; Xu MK; McDonald E; Marshall JC; Fox-Robichaud AE; Charbonney E; Liaw PC
Journal
Intensive Care Medicine Experimental, Vol. 7, No. 1,
Publisher
Springer Nature
Publication Date
December 2019
DOI
10.1186/s40635-019-0251-4
ISSN
2197-425X