The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation Academic Article uri icon

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abstract

  • Key Points This breakthrough involves the role of the aryl hydrocarbon receptor in the expansion and specification of hematopoietic progenitor cells. This work sets a precedent for the use of an in vitro platform for the clinically relevant production of blood products.

authors

  • Smith, Brenden W
  • Rozelle, Sarah S
  • Leung, Amy
  • Ubellacker, Jessalyn
  • Parks, Ashley
  • Nah, Shirley K
  • French, Deborah
  • Gadue, Paul
  • Monti, Stefano
  • Chui, David Hing-kwei
  • Steinberg, Martin H
  • Frelinger, Andrew L
  • Michelson, Alan D
  • Theberge, Roger
  • McComb, Mark E
  • Costello, Catherine E
  • Kotton, Darrell N
  • Mostoslavsky, Gustavo
  • Sherr, David H
  • Murphy, George J

publication date

  • July 18, 2013

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