Journal article
Protocol for a systematic review, meta-analysis, and trial sequential analysis of clinical outcomes following accelerated versus conventional corneal collagen cross-linking for corneal ectasia
Abstract
BackgroundCollagen cross-linking (CXL) is an evolving procedure that enhances the biomechanical rigidity of the cornea and can slow or halt ectatic disease. CXL requires delivery of 5.4 J/cm2 of ultraviolet A (UVA) radiation to a cornea saturated with riboflavin in order to induce cross-link formation. The conventional CXL procedure achieves this fluence by exposing the cornea to a 3 mW/cm2 UVA lamp for 30 min; however, some surgeons have …
Authors
Nath S; Shen C; Koziarz A; Banfield L
Journal
Systematic Reviews, Vol. 8, No. 1,
Publisher
Springer Nature
Publication Date
12 2019
DOI
10.1186/s13643-019-1004-x
ISSN
2046-4053