The Meaning-Making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: a randomized controlled pilot study Academic Article uri icon

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  • OBJECTIVE: This pilot study aimed to provide supportive evidence for the acceptability and usefulness of the Meaning-Making intervention (MMi) in patients newly diagnosed with Stage III or IV ovarian cancer, and to provide estimates of parameters needed to design a full-scale study. METHODS: A randomized controlled trial with 24 patients (12 experimental and 12 control) was conducted. Existential well-being (primary outcome), overall quality of life, distress, anxiety, depression and self-efficacy were measured. RESULTS: Compared to the control group, patients in the experimental group had a better sense of meaning in life at one and three months post-intervention. CONCLUSION: The MMi seems a promising intervention for advanced cancer patients, and a full randomized controlled trial is warranted to further investigate its efficacy.


  • Henry, Melissa
  • Cohen, S Robin
  • Lee, Virginia
  • Sauthier, Philippe
  • Provencher, Diane
  • Drouin, Pierre
  • Gauthier, Philippe
  • Gotlieb, Walter
  • Lau, Susie
  • Drummond, Nancy
  • Gilbert, Lucy
  • Stanimir, Gerald
  • Sturgeon, Jeremy
  • Chasen, Martin
  • Mitchell, Julie
  • Huang, Lina Nuoxin
  • Ferland, Mira-Klode
  • Mayo, Nancy

publication date

  • December 2010

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