Journal article
Noradrenaline inhibits neurogenic propulsive motor patterns but not neurogenic segmenting haustral progression in the rabbit colon
Abstract
BACKGROUND: Excessive sympathetic inhibition may be a cause of colon motor dysfunction. Our aim was to better understand the mechanisms of sympathetic inhibition on colonic motor patterns using the rabbit colon, hypothesizing that noradrenaline selectively inhibits propulsive motor patterns.
METHODS: Changes in motor patterns of the rabbit colon were studied ex vivo using noradrenaline and adrenoceptor antagonists and analyzed using …
Authors
Hanman A; Chen J; Parsons SP; Huizinga JD
Journal
Neurogastroenterology & Motility, Vol. 31, No. 5,
Publisher
Wiley
Publication Date
May 2019
DOI
10.1111/nmo.13567
ISSN
1350-1925