Electron spectroscopic imaging of encapsidated DNA in vaccinia virus Academic Article uri icon

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abstract

  • We have used electron spectroscopic imaging to locate the phosphorus in vaccinia DNA in situ in unstained, ultrathin sections of virions. The phosphorus of the DNA backbone appeared to form a halo on the core periphery surrounding a phosphorus-impoverished central element. These results constrain models for how DNA could be packaged into mature vaccinia particles.

authors

publication date

  • October 1995