Current Thoughts on the Use of Methotrexate in Patients with Psoriasis Journal Articles

abstract

• Background:There are many problems associated with the use of methotrexate in the treatment of psoriasis.Objective:We will attempt to assist the clinician in resolving some of these problems.Methods:This article is a summary of a Round Table Discussion on methotrexate held at the Canadian Dermatology Association meeting at Whistler, BC, July 1995; of a Continuing Medical Education meeting on methotrexate at Langdon Hall, Cambridge, ON, May 1996; and our review of the pertinent literature.Results:We recommend routine folic acid supplementation in patients receiving methotrexate. A baseline pretreatment liver biopsy is probably not indicated in patients without clinical or laboratory evidence of liver disease; and patients on 15 mg or less of methotrexate per week with normal liver function may not need liver biopsy.Conclusion:Liver biopsy of patients on methotrexate for psoriasis may not be necessary.

authors

• Rosenthal, Donald
• Guenther, Lyn
• Kelly, James

status

• published 

publication date

• July 1997

has subject area

• Dermatology & Venereal Diseases (Science Metrix)

published in

• Journal of Cutaneous Medicine and Surgery  Journal

keywords

• 32 Biomedical and Clinical Sciences
• 3202 Clinical Sciences
• Autoimmune Disease
• Chronic Liver Disease and Cirrhosis
• Digestive Diseases
• Liver Disease
• Oral and gastrointestinal
• Psoriasis

Digital Object Identifier (DOI)

• 10.1177/120347549700200111

start page

• 41

end page

• 46

volume

• 2

issue

• 1