Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis Academic Article uri icon

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  • ObjectiveTo determine the benefits and harms of subacromial decompression surgery in adult patients with subacromial pain syndrome lasting for more than 3 months.DesignSystematic review with meta-analysis.Main outcome measuresPain, physical function and health-related quality of life.Data sourcesSystematic searches for benefits and harms were conducted to 23 July 2018 in MEDLINE, Embase, PubMed, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cumulative Index to Nursing and Allied Health Literature, Physiotherapy Evidence Database,, WHO International Clinical Trials Registry Platform, Database of Abstracts of Reviews of Effects, and Health Technology Assessment.Eligibility criteria for selecting studiesRandomised controlled trials comparing subacromial decompression surgery for subacromial pain syndrome with any other treatment(s). For harms, we included prospective cohort studies.Review methodsTwo reviewers independently determined eligibility, extracted the data and assessed the risk of bias of eligible studies. Thirty patients seeking primary or outpatient care for subacromial pain syndrome and a parallel guideline committee (BMJ Rapid Recommendations) provided input regarding systematic review design and interpretation.ResultsThere was high certainty evidence of no additional benefit of subacromial decompression surgery over placebo surgery in reducing pain at 1 year following surgery (mean difference [MD] −0.26, 95% CI −0.84 to 0.33, minimally important difference [MID] 1.5) or improving physical function at 1–2 years (MD 2.8, 95% CI −1.4 to 6.9, MID 8.3). There was moderate certainty evidence for no additional benefit of subacromial decompression surgery on health-related quality of life at 1 year (MD −0.03 points, 95% CI −0.11 to 0.06, MID 0.07). There was moderate certainty evidence for six serious harms per 1000 (95% CI 5 to 7) patients undergoing subacromial decompression.ConclusionSubacromial decompression surgery provided no important benefit compared with placebo surgery or exercise therapy, and probably carries a small risk of serious harms.Systematic reviewregistration numberCRD42018086862.


  • Lähdeoja, Tuomas
  • Karjalainen, Teemu
  • Jokihaara, Jarkko
  • Salamh, Paul
  • Kavaja, Lauri
  • Agarwal, Arnav
  • Winters, Marinus
  • Buchbinder, Rachelle
  • Guyatt, Gordon
  • Vandvik, Per Olav
  • Ardern, Clare L

publication date

  • June 2020