Journal article
Intestinal organoids: A new paradigm for engineering intestinal epithelium in vitro
Abstract
In recent years, the advent of intestinal organoid culture systems has revolutionized in vitro studies of the small intestine epithelium. Intestinal organoids are derived from self-organizing and self-renewing intestinal stem cells and closely recapitulate the native intestinal epithelium. They therefore represent a more physiologically-relevant in vitro model than conventional cell cultures for studying intestinal development, biology and …
Authors
Rahmani S; Breyner NM; Su H-M; Verdu EF; Didar TF
Journal
Biomaterials, Vol. 194, , pp. 195–214
Publisher
Elsevier
Publication Date
February 2019
DOI
10.1016/j.biomaterials.2018.12.006
ISSN
0142-9612