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Activation and Inhibition of Virus and Interferon:...
Journal article

Activation and Inhibition of Virus and Interferon: The Herpesvirus Story

Abstract

Viral infection of a host leads to induction of an immune system attack against the virus along with a counterattack by the virus against the host. Interferons are highly upregulated upon viral infection and function as key regulators of the host innate defense system. Whereas many RNA viruses are sensitive to the effects of interferon, several of the large DNA viruses are relatively resistant, given their capacity to encode proteins that …

Authors

Mossman KL

Journal

Viral Immunology, Vol. 15, No. 1, pp. 3–15

Publisher

Mary Ann Liebert

Publication Date

March 2002

DOI

10.1089/088282402317340198

ISSN

0882-8245