Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity" Academic Article

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abstract

Herbert et al . (Reports, 14 April 2006, p. 279) found that the rs7566605 genetic variant, located upstream of the INSIG2 gene, was consistently associated with increased body mass index. However, we found no evidence of association between rs7566605 and body mass index in two large ethnically homogeneous population-based cohorts. On the contrary, an opposite tendency was observed.

authors

Meyre, David Jean-Claude
Loos, Ruth JF
Barroso, Inês
O'Rahilly, Stephen
Wareham, Nicholas J

status

published

publication date

January 12, 2007

has subject area

Adult (MeSH)
Alleles (MeSH)
Body Mass Index (MeSH)
Cohort Studies (MeSH)
European Continental Ancestry Group (MeSH)
Female (MeSH)
General Science & Technology (Science Metrix)
Genes, Recessive (MeSH)
Genetic Predisposition to Disease (MeSH)
Genetic Variation (MeSH)
Genotype (MeSH)
Humans (MeSH)
Intracellular Signaling Peptides and Proteins (MeSH)
Male (MeSH)
Membrane Proteins (MeSH)
Obesity (MeSH)
Polymorphism, Single Nucleotide (MeSH)
White People (MeSH)

published in

Science Journal