Comment on "A Common Genetic Variant Is Associated with Adult and Childhood Obesity" Academic Article uri icon

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abstract

  • Contrary to the findings of Herbert et al. (Reports, 14 April 2006, p. 279), homozygous carriers of the C allele of the rs7566605 variant near the INSIG2 gene did not exhibit a significantly increased risk for obesity in a large population-based cross-sectional German study. A subgroup analysis, however, revealed that this allele significantly increased the risk for obesity in already overweight individuals.

authors

  • Meyre, David Jean-Claude
  • Rosskopf, Dieter
  • Bornhorst, Alexa
  • Rimmbach, Christian
  • Schwahn, Christian
  • Kayser, Alexander
  • Krüger, Anne
  • Tessmann, Grietje
  • Geissler, Ingrid
  • Kroemer, Heyo K
  • Völzke, Henry

publication date

  • January 12, 2007