Journal article
Injectable and Degradable Poly(Oligoethylene glycol methacrylate) Hydrogels with Tunable Charge Densities as Adhesive Peptide-Free Cell Scaffolds
Abstract
Injectable, dual-responsive, and degradable poly(oligo ethylene glycol methacrylate) (POEGMA) hydrogels are demonstrated to offer potential for cell delivery. Charged groups were incorporated into hydrazide and aldehyde-functionalized thermoresponsive POEGMA gel precursor polymers via the copolymerization of N,N'-dimethylaminoethyl methacrylate (DMAEMA) or acrylic acid (AA) to create dual-temperature/pH-responsive in situ gelling hydrogels that …
Authors
Bakaic E; Smeets NMB; Badv M; Dodd M; Barrigar O; Siebers E; Lawlor M; Sheardown H; Hoare T
Journal
ACS Biomaterials Science & Engineering, Vol. 4, No. 11, pp. 3713–3725
Publisher
American Chemical Society (ACS)
Publication Date
November 12, 2018
DOI
10.1021/acsbiomaterials.7b00397
ISSN
2373-9878