Hemoglobin QIndia, α64(E l3) Asp→His, and β- Thalassemiaina Canadian Family Academic Article uri icon

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abstract

  • Cellulose acetate electrophoresis at pH 8.4 showed a hemoglobin variant with the mobility of hemoglobin S in a Canadian family. Sequence analysis revealed that histidine was substituted for aspartic acid at position 64 in the alpha-chain. This variant was found in association with a beta-thalassemia trait condition.

authors

  • Ali, Mahmoud
  • Schmidt, Robert M
  • Bechtel, Katherine C
  • Moo-Penn, Winston F

publication date

  • August 1, 1976