Hemoglobin QIndia, α64(E l3) Asp→His, and β-...

Hemoglobin QIndia, α64(E l3) Asp→His, and β- Thalassemiaina Canadian Family

Abstract

Cellulose acetate electrophoresis at pH 8.4 showed a hemoglobin variant with the mobility of hemoglobin S in a Canadian family. Sequence analysis revealed that histidine was substituted for aspartic acid at position 64 in the alpha-chain. This variant was found in association with a beta-thalassemia trait condition.

Authors

Schmidt RM; Bechtel KC; Moo-Penn WF

Journal

American Journal of Clinical Pathology, Vol. 66, No. 2, pp. 446–448

Publisher

Oxford University Press (OUP)

Publication Date

August 1, 1976

DOI

10.1093/ajcp/66.2.446

ISSN

0002-9173

Associated Experts

Mahmoud Ali

Professor Emeritus, Faculty of Health Sciences

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