Hemoglobin Q_India, α₆₄(E l3) Asp→His, and β- Thalassemiaina Canadian Family Journal Articles

abstract

• Cellulose acetate electrophoresis at pH 8.4 showed a hemoglobin variant with the mobility of hemoglobin S in a Canadian family. Sequence analysis revealed that histidine was substituted for aspartic acid at position 64 in the alpha-chain. This variant was found in association with a beta-thalassemia trait condition.

authors

• Ali, Mahmoud
• Schmidt, Robert M
• Bechtel, Katherine C
• Moo-Penn, Winston F

status

• published 

publication date

• August 1, 1976

has subject area

• 11 Medical and Health Sciences (FoR)
• Amino Acids (MeSH)
• Child, Preschool (MeSH)
• Hemoglobins, Abnormal (MeSH)
• Humans (MeSH)
• India (MeSH)
• Male (MeSH)
• Pathology (Science Metrix)
• Thalassemia (MeSH)

published in

• American Journal of Clinical Pathology  Journal

keywords

• Amino Acids
• Child, Preschool
• Hemoglobins, Abnormal
• Humans
• India
• Male
• Thalassemia

Digital Object Identifier (DOI)

• 10.1093/ajcp/66.2.446

PubMed ID

• 949043

start page

• 446

end page

• 448

volume

• 66

issue

• 2