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Graphene-DNAzyme-based fluorescent biosensor for...
Journal article

Graphene-DNAzyme-based fluorescent biosensor for Escherichia coli detection

Abstract

Herein we describe the use of a new DNAzyme/graphene hybrid material as a biointerfaced sensing platform for optical detection of pathogenic bacteria. The hybrid consists of a colloidal graphene nanomaterial and an Escherichia coli-activated RNA-cleaving DNAzyme and is prepared via non-covalent self-assembly of the DNAzyme onto the graphene surface. Exposure of the hybrid material to E. coli-containing samples results in the release of the …

Authors

Liu M; Zhang Q; Brennan JD; Li Y

Journal

MRS Communications, Vol. 8, No. 3, pp. 687–694

Publisher

Springer Nature

Publication Date

September 2018

DOI

10.1557/mrc.2018.97

ISSN

2159-6859

Labels

McMaster Research Centers and Institutes (RCI)