Journal article
Abnormal Contractile Response of Aortas from Spontaneously Hypertensive Rats to Ca2+ After Depletion of Ca2+ in Ca2+-Free Medium
Abstract
Vascular responses of aortic rings from spontaneously hypertensive rats (SHR) were compared to those of the normotensive Wistar-Kyoto rats (WKY) in three sets of experimental protocols. The responses to cumulative doses of KCl indicated that SHR aortic rings were hyperresponsive to low but not high doses of KCl compared to WKY aortic rings. After Ca depletion by prolonged incubation of the rat aortic rings with Ca2+-free, EGTA containing …
Authors
Guan YY; Kwan CY
Journal
American Journal of Hypertension, Vol. 2, No. 8, pp. 643–646
Publisher
Oxford University Press (OUP)
Publication Date
August 1, 1989
DOI
10.1093/ajh/2.8.643
ISSN
0895-7061