Journal article
REGULATION OF VASCULAR CONTRACTION BY IONIC MATRIX SURFACES OF THE SMOOTH MUSCLE CELL: CHANGES IN SHR?
Abstract
1. KCl-induced contractions in aortic rings of spontaneously hypertensive rats (SHR) and two normotensive strains, Sprague-Dawley (SD) and Wistar-Kyoto (WKY) rats, were studied. 2. The contraction elicited by isotonic Na-free, KCl solution containing 2.5 mmol/L Ca and 1 mmol/L Mg was concentration-dependently inhibited by Na and K. Maximal inhibition was induced by 20 mmol/L NaCl in WKY and SHR (65 and 85%, respectively) and by 60 mmol/L NaCl …
Authors
Kravtsov GM; Kwan CY
Journal
Clinical and experimental pharmacology & physiology. Supplement, Vol. 22, No. 1, pp. s237–s239
Publisher
Wiley
Publication Date
November 1995
DOI
10.1111/j.1440-1681.1995.tb02898.x
ISSN
0143-9294