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Calcium competes with zinc for a channel mechanism...
Journal article

Calcium competes with zinc for a channel mechanism on the brush border membrane of piglet intestine

Abstract

Interactions between Ca(+2) and Zn(+2) at the intestinal brush border membrane occur via unclear mechanisms. We hypothesized that Zn(+2) and Ca(+2) are transported across the brush border membrane via a multidivalent metal channel. Using brush border membrane vesicles (BBMV) prepared from intestines of 8 sow-fed piglets, we sought to determine whether Ca(+2) competes with Zn(+2) for uptake. Extravesicular Zn(+2) was removed with …

Authors

Bertolo RFP; Bettger WJ; Atkinson SA

Journal

The Journal of Nutritional Biochemistry, Vol. 12, No. 2, pp. 66–72

Publisher

Elsevier

Publication Date

February 2001

DOI

10.1016/s0955-2863(00)00125-x

ISSN

0955-2863