Quantifying the competing relationship between durability and kinematics of total knee replacements using multiobjective design optimization and validated computational models

Durability and kinematics are two critical factors which must be considered during total knee replacement (TKR) implant design. It is hypothesized, however, that there exists a competing relationship between these two performance measures, such that improvement of one requires sacrifice with respect to the other. No previous studies have used rigorous and systematic methods to quantify this relationship. During this study, multiobjective design …