The use of labelled analogues for the determination of mass spectrometric fragmentation mechanisms of cannabinoids. A re‐investigation of the formation of the most abundant fragment ion [C15,H19,O2]+ in Δ1(6)tetrahydrocannabinol

AbstractThe routes leading to the formation of the most prominent fragment ion [C15H19O2]+ (m/e 231) in the cannabinoid Δ1(6) tetrahydrocannabinol were investigated with the aid of deuterium labelled compounds. A previously proposed mechanism for the two‐step process could be confirmed, but the mechanism for the one‐step route had to be revised.

The use of labelled analogues for the determination of mass spectrometric fragmentation mechanisms of cannabinoids. A re‐investigation of the formation of the most abundant fragment ion [C₁₅,H₁₉,O₂]⁺ in Δ¹⁽⁶⁾tetrahydrocannabinol Journal Articles