Fanconi's anemia: a clinico-hematological and cytogenetic study. Journal Articles uri icon

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abstract

  • Eleven patients with typical features of Fanconi's anemia with cytogenetic studies were evaluated. Cytogenetic abnormalities was seen in all but one patient. Two patients had acute non-lymphoblastic leukemia (ANLL) and nine had Fanconi's anemia (FA). All patients with FA responded to oxymetholone and are well with a median follow up of 38.6 months. Both patients with ANLL died. This study stresses the need of an accurate cytogenetic analysis in FA patients along with a clinicohematological correlation.

authors

  • Athale, Uma
  • Rao, SR
  • Kadam, PR
  • Gladstone, B
  • Nair, CN
  • Kurkure, PA
  • Advani, SH

publication date

  • September 1991