Journal article
Effect of awareness of a randomized controlled trial on use of experimental therapy.
Abstract
CONTEXT: Use of experimental therapies during but outside of randomized controlled trials (RCTs) has not been studied.
OBJECTIVE: To determine whether initiation of an RCT leads to increased use of the experimental therapy outside the trial.
Authors
Clark WF; Garg AX; Blake PG; Rock GA; Heidenheim AP; Sackett DL
Journal
JAMA: The Journal of the American Medical Association, Vol. 290, No. 10, pp. 1351–1355
Publisher
American Medical Association (AMA)
Publication Date
September 10, 2003
DOI
10.1001/jama.290.10.1351
ISSN
0098-7484