Incidence of arthritis in a prospective cohort of psoriasis patients Academic Article uri icon

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abstract

  • OBJECTIVE: Epidemiologic studies about the incidence of psoriatic arthritis (PsA) are limited to a few population-based studies. There are limited data regarding the incidence of PsA in patients with psoriasis. We aimed to determine the incidence of PsA among a prospective cohort of psoriasis patients. METHODS: The setting is a prospective longitudinal cohort study of psoriasis patients without arthritis. The patients are assessed annually by a rheumatologist in order to detect the onset of arthritis. We summarize the results of 4 years of followup and report the cumulative incidence of PsA from the time of entry to the study that was estimated using an event per person-years analysis and a nonparametric analysis. RESULTS: Three hundred thirteen psoriasis patients that had at least 1 year of followup were included in the analysis. The annual incidence rate was found to be 1.87 (95% confidence interval 0.71-3.03) PsA cases per 100 psoriasis patients. CONCLUSION: The incidence rate of PsA in patients with psoriasis may be higher than previously reported, particularly among patients with moderate to severe psoriasis.

authors

  • Eder, Lihi
  • Chandran, Vinod
  • Shen, Hua
  • Cook, Richard
  • Shanmugarajah, Sutha
  • Rosen, Cheryl F
  • Gladman, Dafna D

publication date

  • April 2011