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Acute stressors stimulate ion secretion and...

Journal article

Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine

Abstract

Wistar-Kyoto rats were subjected to 4 h restraint stress (RS) or cold restraint stress (CRS), and jejunal tissues were examined in Ussing chambers for alterations in transport functions compared with tissues from unstressed control rats. The baseline short-circuit current (Isc) was significantly elevated in tissues from RS (approximately 50%) and CRS (100%). Substitution of Cl- eliminated the abnormality, suggesting that stress stimulates Cl- …

Authors

Saunders PR; Kosecka U; McKay DM; Perdue MH

Journal

American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 267, No. 5, pp. G794–G799

Publisher

American Physiological Society

Publication Date

November 1, 1994

DOI

10.1152/ajpgi.1994.267.5.g794

ISSN

0193-1857

Associated Experts

Mary Perdue

Professor Emeritus, Faculty of Health Sciences

Labels

Medical Subject Headings (MeSH)

Acute Disease Animals Biological Transport Corticosterone In Vitro Techniques Intestinal Mucosa Ions Jejunum Male Permeability Rats Rats, Inbred WKY Stress, Physiological

Fields of Research (FoR)

3202 Clinical sciences 3208 Medical physiology

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