Journal article
Randomised controlled trials in oncology closed early for benefit: Trends in methodology, results, and interpretation
Abstract
PURPOSE: To assess methodology, results and interpretation of oncology randomised controlled trials closed early for benefit (RCTCEB).
METHODS: Structured literature search (1950-2008) to identify all published oncology RCTCEB. We then searched for related follow-up articles and conference abstracts to evaluate whether study results and conclusions changed with longer follow-up. A standardised data abstraction process captured information …
Authors
Booth CM; Ohorodnyk P; Zhu L; Tu D; Meyer RM
Journal
European Journal of Cancer, Vol. 47, No. 6, pp. 854–863
Publisher
Elsevier
Publication Date
April 2011
DOI
10.1016/j.ejca.2010.12.005
ISSN
0959-8049