Developmental changes in the gonadotropin releasing hormone neuron of the female rabbit: effects of tamoxifen citrate and pregnant mare serum gonadotropin

Developmental changes in immunostained gonadotropin releasing hormone neurons were demonstrated in female rabbits assigned to the following treatment groups: (i) tamoxifen citrate, 10 mg.kg-1 x day-1, in sesame seed oil (vehicle) (n = 24) or (ii) vehicle alone (control, n = 24) for 108 days; and (iii) 50 IU of pregnant mare serum gonadotropin on postnatal days 22 and 25 (n = 24) or vehicle on nontreatment days. Treatments had no effect on the …