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Journal article

Subchronic Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Modulates the Pathophysiology of Endometriosis in the Cynomolgus Monkey

Abstract

An increase in the incidence and severity of endometriosis following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was a serendipitous finding in a reproductive toxicology study in rhesus monkeys. The purpose of this study was to investigate the effects of subchronic exposure to TCDD on the survival and growth of surgically implanted endometrial fragments. Endometrial fragments of equal size (4 x 1 mm(2)) were auto-transplanted to …

Authors

Yang JZ; Agarwal SK; Foster WG

Journal

Toxicological Sciences, Vol. 56, No. 2, pp. 374–381

Publisher

Oxford University Press (OUP)

Publication Date

August 1, 2000

DOI

10.1093/toxsci/56.2.374

ISSN

1096-6080