Journal article
The Importance of Quality of Primary Studies in Producing Unbiased Systematic Reviews
Abstract
BACKGROUND: Traditional and largely qualitative reviews of evidence are now giving way to much more structured systematic overviews that use a quantitative method to calculate the overall effect of treatment. The latter approach is dependent on the quality of primary studies, which may introduce bias if they are of poor methodologic quality.
OBJECTIVE: To test the hypothesis that the inclusion of poor-quality trials in meta-analyses would bias …
Authors
Khan KS; Daya S; Jadad A
Journal
JAMA Internal Medicine, Vol. 156, No. 6, pp. 661–666
Publisher
American Medical Association (AMA)
Publication Date
March 25, 1996
DOI
10.1001/archinte.1996.00440060089011
ISSN
2168-6106