Granulocytes do not have surface ABO antigens Journal Articles

abstract

• There is disagreement whether granulocytes have ABO antigens on their surfaces. We investigated this issue using pure populations of washed granulocytes from healthy individuals of known ABO, Lewis, and secretor phenotypes. The presence of ABO antigens on granulocytes was sought using four different techniques: a granulocyte‐red cell mixed agglutination assay; a microleukoagglutination assay; a microgranulocyte cytotoxicity assay; and an immunoradiometric assay for granulocyte‐associated IgG. Both fixed and unfixed granulocytes were tested. All tests were negative. Granulocytes do not have ABO antigens on their surfaces.

authors

• Kelton, John
• Bebenek, G

status

• published 

publication date

• November 12, 1985

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• 1103 Clinical Sciences (FoR)
• 1107 Immunology (FoR)
• ABO Blood-Group System (MeSH)
• Antigens, Surface (MeSH)
• Cardiovascular System & Hematology (Science Metrix)
• Cytotoxicity Tests, Immunologic (MeSH)
• Granulocytes (MeSH)
• Hemagglutination Tests (MeSH)
• Humans (MeSH)
• Immunoglobulin G (MeSH)
• Methods (MeSH)
• Microchemistry (MeSH)
• Radioimmunoassay (MeSH)

published in

• Transfusion  Journal

keywords

• ABO Blood-Group System
• Antigens, Surface
• Cytotoxicity Tests, Immunologic
• Granulocytes
• Hemagglutination Tests
• Humans
• Immunoglobulin G
• Methods
• Microchemistry
• Radioimmunoassay

Digital Object Identifier (DOI)

• 10.1046/j.1537-2995.1985.25686071432.x

PubMed ID

• 4071602

start page

• 567

end page

• 569

volume

• 25

issue

• 6