Management of idiopathic thrombocytopenic purpura in pregnancy Journal Articles

abstract

• Idiopathic thrombocytopenic purpura (ITP) is a relatively common autoimmune disorder among women of child-bearing age. It has a frequency of approximately one to two per 1,000 live births, accounting for about 3% of all cases of maternal thrombocytopenia at delivery. ITP in pregnancy necessitates the management of two patients, the mother and her baby; hence, the close collaboration of a multidisciplinary group composed of a hematologist, obstetrician, and pediatrician is essential. Our understanding of thrombocytopenia in pregnancy has evolved considerably over the last decade, yet the optimal diagnostic and treatment strategies for ITP in pregnancy continues to create controversy. In reviewing the recent literature, there is resurgence in the trend towards treating these patients in a more conservative fashion. This review will summarize the current approach to the diagnosis of ITP in pregnancy, as well as explore the pertinent and controversial issues of investigation and management.

authors

• Gill, Karamjit K
• Kelton, John

status

• published 

publication date

• July 2000

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• Diagnosis, Differential (MeSH)
• Disease Management (MeSH)
• Female (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• Infant, Newborn (MeSH)
• Intracranial Hemorrhages (MeSH)
• Male (MeSH)
• Pregnancy (MeSH)
• Pregnancy Complications, Hematologic (MeSH)
• Purpura, Thrombocytopenic, Idiopathic (MeSH)
• Thrombocytopenia (MeSH)

published in

• Seminars in Hematology  Journal

keywords

• Diagnosis, Differential
• Disease Management
• Female
• Humans
• Infant, Newborn
• Intracranial Hemorrhages
• Male
• Pregnancy
• Pregnancy Complications, Hematologic
• Purpura, Thrombocytopenic, Idiopathic
• Thrombocytopenia

Digital Object Identifier (DOI)

• 10.1016/s0037-1963(00)90106-9

PubMed ID

• 10942222

start page

• 275

end page

• 289

volume

• 37

issue

• 3