Journal article
Fluorogenic DNAzyme Probes as Bacterial Indicators
Abstract
Lighting up bacteria: An RNA‐cleaving fluorescent DNAzyme (RFD) can produce a fluorescent signal in the crude extracellular mixture generated by live bacterial cells (see picture). These DNAzymes cleave a lone RNA linkage (R) embedded in a DNA chain and flanked by nucleotides labeled with a fluorophore (F) and a quencher (Q).
Authors
Ali MM; Aguirre SD; Lazim H; Li Y
Journal
Angewandte Chemie International Edition, Vol. 50, No. 16, pp. 3751–3754
Publisher
Wiley
Publication Date
April 11, 2011
DOI
10.1002/anie.201100477
ISSN
1433-7851