Aptamers and Small Molecules Play Tug of War

Abstract

Recently, aptamers began to emerge as therapeutics. In this issue of Chemistry & Biology, Famulok and colleagues [1] present a twist on this concept, using an enzyme-inhibiting aptamer as a tool to screen for small molecules that block HIV replication.

Authors

Fowler CC; Li Y

Journal

Cell Chemical Biology, Vol. 14, No. 7, pp. 736–738

Publisher

Elsevier

Publication Date

July 30, 2007

DOI

10.1016/j.chembiol.2007.07.003

ISSN

2451-9456

Associated Experts

Yingfu Li

Professor, Faculty of Health Sciences

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