Aptamers and Small Molecules Play Tug of War Journal Articles

abstract

• Recently, aptamers began to emerge as therapeutics. In this issue of Chemistry & Biology, Famulok and colleagues [1] present a twist on this concept, using an enzyme-inhibiting aptamer as a tool to screen for small molecules that block HIV replication.

authors

• Fowler, Casey C
• Li, Yingfu

status

• published 

publication date

• July 2007

has subject area

• Aptamers, Nucleotide (MeSH)
• Fluorescence Resonance Energy Transfer (MeSH)
• HIV (MeSH)
• Reverse Transcriptase Inhibitors (MeSH)
• Virus Replication (MeSH)

published in

• Cell Chemical Biology  Journal

keywords

• Aptamers, Nucleotide
• Fluorescence Resonance Energy Transfer
• HIV
• Reverse Transcriptase Inhibitors
• Virus Replication

Digital Object Identifier (DOI)

• 10.1016/j.chembiol.2007.07.003

PubMed ID

• 17656309

start page

• 736

end page

• 738

volume

• 14

issue

• 7