Journal article
Thymic stromal lymphopoietin: a central regulator of allergic asthma
Abstract
INTRODUCTION: Epithelial cell-derived mediators have emerged as key players for instigating local remodeling and the associated cellular inflammation in asthmatic airways. In particular, the epithelial-derived cytokine, thymic stromal lymphopoietin (TSLP), has been identified as a master switch for allergic inflammation.
AREAS COVERED: TSLP is expressed by structural and immune cells at the site of allergen entry in the airways. Stimuli for …
Authors
Watson B; Gauvreau GM
Journal
Expert Opinion on Therapeutic Targets, Vol. 18, No. 7, pp. 771–785
Publisher
Taylor & Francis
Publication Date
July 2014
DOI
10.1517/14728222.2014.915314
ISSN
1472-8222