Quantifying iron content in magnetic resonance imaging Journal Articles

abstract

• Measuring iron content has practical clinical indications in the study of diseases such as Parkinson's disease, Huntington's disease, ferritinopathies and multiple sclerosis as well as in the quantification of iron content in microbleeds and oxygen saturation in veins. In this work, we review the basic concepts behind imaging iron using T2, T2*, T2', phase and quantitative susceptibility mapping in the human brain, liver and heart, followed by the applications of in vivo iron quantification in neurodegenerative diseases, iron tagged cells and ultra-small superparamagnetic iron oxide (USPIO) nanoparticles.

authors

• Ghassaban, Kiarash
• Liu, Saifeng
• Jiang, Caihong
• Haacke, Mark

status

• published 

publication date

• February 2019

has subject area

• 11 Medical and Health Sciences (FoR)
• 17 Psychology and Cognitive Sciences (FoR)
• Animals (MeSH)
• Brain (MeSH)
• Brain Chemistry (MeSH)
• Ferric Compounds (MeSH)
• Humans (MeSH)
• Image Processing, Computer-Assisted (MeSH)
• Iron (MeSH)
• Liver (MeSH)
• Magnetic Resonance Imaging (MeSH)
• Magnetite Nanoparticles (MeSH)
• Myocardium (MeSH)
• Neurodegenerative Diseases (MeSH)
• Neurology & Neurosurgery (Science Metrix)

published in

• NeuroImage  Journal

keywords

• Animals
• Brain
• Brain Chemistry
• Ferric Compounds
• Humans
• Image Processing, Computer-Assisted
• Iron
• Iron quantification
• Iron tagged cells
• Liver
• Magnetic Resonance Imaging
• Magnetic resonance imaging
• Magnetite Nanoparticles
• Multiple sclerosis
• Myocardium
• Neurodegenerative Diseases
• Parkinson's disease
• USPIO contrast agents

Digital Object Identifier (DOI)

• 10.1016/j.neuroimage.2018.04.047

PubMed ID

• 29702183

start page

• 77

end page

• 92

volume

• 187