keywords Allopatric speciation Antifungal drug resistance Biologicalspecies CRYPTOCOCCUS-NEOFORMANS Clonality Cryptococcus neoformans DNA BARCODE EVOLUTION Ecologicalspecies Fungi Gene genealogy Genome rearrangements Genomics HYBRIDIZATION Humanmicrobiome Humanmycobiome Hybridization Life Sciences & Biomedicine Metagenomics Microbiology Morphologic species Phylogeneticspecies Population genomics RECOMBINATION Recombination Science & Technology Signature sequences Speciation genes Species concepts Sympatric speciation