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The clinical impact of copy number variants in...
Journal article

The clinical impact of copy number variants in inherited bone marrow failure syndromes

Abstract

Inherited bone marrow failure syndromes comprise a genetically heterogeneous group of diseases with hematopoietic failure and a wide array of physical malformations. Copy number variants were reported in some inherited bone marrow failure syndromes. It is unclear what impact copy number variants play in patients evaluated for a suspected diagnosis of inherited bone marrow failure syndromes. Clinical and genetic data of 323 patients from the …

Authors

Waespe N; Dhanraj S; Wahala M; Tsangaris E; Enbar T; Zlateska B; Li H; Klaassen RJ; Fernandez CV; Cuvelier GDE

Journal

npj Genomic Medicine, Vol. 2, No. 1,

Publisher

Springer Nature

Publication Date

May 10, 2017

DOI

10.1038/s41525-017-0019-2

ISSN

2056-7944