Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels Academic Article uri icon

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abstract

  • Key Points Three independent association signals at ADAMTS13 and smoking were identified as major predictors of plasma ADAMTS13 levels. Evidence was presented that 2 nonsynonymous ADAMTS13 variants were driving the variation of plasma ADAMTS13 concentrations.

authors

  • Ma, Qianyi
  • Jacobi, Paula M
  • Emmer, Brian T
  • Kretz, Colin
  • Ozel, Ayse Bilge
  • McGee, Beth
  • Kimchi-Sarfaty, Chava
  • Ginsburg, David
  • Li, Jun Z
  • Desch, Karl C

publication date

  • June 27, 2017