Multiple overlapping systematic reviews facilitate the origin of disputes: the case of thrombolytic therapy for pulmonary embolism

Abstract

OBJECTIVE: To explore disagreements in multiple systematic reviews (SRs) assessing the benefit-to-harm ratio of thrombolytic therapy in patients with intermediate-risk pulmonary embolism (PE). STUDY DESIGN AND SETTING: MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, and Database of Abstracts and Reviews of Effectiveness were searched up to April 14, 2016. We included SRs and guidelines that evaluated thrombolytic therapy, compared …

Authors

Riva N; Puljak L; Moja L; Ageno W; Schünemann H; Magrini N; Squizzato A

Journal

Journal of Clinical Epidemiology, Vol. 97, , pp. 1–13

Publisher

Elsevier

Publication Date

May 2018

DOI

10.1016/j.jclinepi.2017.11.012

ISSN

0895-4356

Associated Experts

Holger Schunemann

Professor Emeritus, Faculty of Health Sciences

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