Journal article
Capturing the State Transitions of Seizure-Like Events using Hidden Markov Models
Abstract
The purpose of this study was to investigate the number of states present in the progression of a seizure-like event (SLE). Of particular interest is to determine if there are more than two clearly defined states, as this would suggest that there is a distinct state preceding an SLE. Whole-intact hippocampus from C57/BL mice was used to model epileptiform activity induced by the perfusion of a low Mg(2+)/high K(+) solution while extracellular …
Authors
Guirgis M; Serletis D; Carlen PL; Bardakjian BL
Journal
Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Vol. 2011, , pp. 2061–2064
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publication Date
2011
DOI
10.1109/iembs.2011.6090381
ISSN
1557-170X