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Silent but deadly: IS200 promotes pathogenicity in...
Journal article

Silent but deadly: IS200 promotes pathogenicity in Salmonella Typhimurium

Abstract

Bacterial transposons were long thought of as selfish mobile genetic elements that propagate at the expense of 'host' bacterium fitness. However, limited transposition can benefit the host organism by promoting DNA rearrangements and facilitating horizontal gene transfer. Here we discuss and provide context for our recently published work which reported the surprising finding that an otherwise dormant transposon, IS200, encodes a regulatory RNA …

Authors

Ellis MJ; Carfrae LA; Macnair CR; Trussler RS; Brown ED; Haniford DB

Journal

RNA Biology, Vol. 15, No. 2, pp. 176–181

Publisher

Taylor & Francis

Publication Date

February 1, 2018

DOI

10.1080/15476286.2017.1403001

ISSN

1547-6286