Hydrogel Microspheres by Thermally Induced Coacervation of Poly(N,N-dimethylacrylamide-c o-glycidyl methacrylate) Aqueous Solutions

Aqueous solutions of poly(N,N-dimethacrylamide-co-glycidyl methacrylate) (DMA−GMA) are shown to undergo liquid−liquid phase separation upon heating. The phase transition temperatures as measured by the cloud point method decreased with increasing levels of the hydrophobic GMA comonomer. The initially formed coacervate microdroplets could be cross-linked by addition of polyamines. The morphology of the resulting hydrogel microspheres depends on …