Journal article
The stability of enamine crosslinks formed from acetoacetate/amine in synthetic hydrogels
Abstract
This paper examines the reversible enamine crosslinking reaction between poly-l-lysine (PLL) and poly (methacrylic acid-co-2[methacryloyloxy]ethyl acetoacetate) (70:30 mol%, A70), used to form crosslinked networks for cell encapsulation. Comparison of polymeric and small-molecule reactants showed that the equilibrium formation of enamine from amine and acetoacetate in water [0.02 M each] increased from 1 to 12 mol% upon going from small …
Authors
Mohajeri S; Burke NAD; Stöver HDH
Journal
Polymer Degradation and Stability, Vol. 114, , pp. 94–104
Publisher
Elsevier
Publication Date
April 2015
DOI
10.1016/j.polymdegradstab.2015.01.027
ISSN
0141-3910