Biosynthesis of Streptolydigin:  Origin of the Oxygen Atoms Academic Article

abstract

• [Structure: see text] Biosynthetic incorporations of [13C,18O]-labeled precursors into streptolydigin reveal the origin of the oxygen atoms, limiting the possible pathways for acyltetramic acid ring assembly and for formation of the bicyclic ketal.

authors

• Chen, Hao
• Olesen, Solveig G
• Harrison, Paul

status

• published 

publication date

• November 9, 2006

has subject area

• 03 Chemical Sciences (FoR)
• Aminoglycosides (MeSH)
• Molecular Structure (MeSH)
• Organic Chemistry (Science Metrix)
• Oxygen (MeSH)
• Oxygen Isotopes (MeSH)
• Streptomyces (MeSH)

published in

• Organic Letters  Journal

keywords

• Aminoglycosides
• Molecular Structure
• Oxygen
• Oxygen Isotopes
• Streptomyces

Digital Object Identifier (DOI)

• 10.1021/ol0621304

PubMed ID

• 17078710

start page

• 5329

end page

• 5332

volume

• 8

issue

• 23