Journal article
Evolution of Salmonella-Host Cell Interactions through a Dynamic Bacterial Genome
Abstract
Salmonella Typhimurium has a broad arsenal of genes that are tightly regulated and coordinated to facilitate adaptation to the various host environments it colonizes. The genome of Salmonella Typhimurium has undergone multiple gene acquisition events and has accrued changes in non-coding DNA that have undergone selection by regulatory evolution. Together, at least 17 horizontally acquired pathogenicity islands (SPIs), prophage-associated genes, …
Authors
Ilyas B; Tsai CN; Coombes BK
Journal
Frontiers in Cellular and Infection Microbiology, Vol. 7, ,
Publisher
Frontiers
DOI
10.3389/fcimb.2017.00428
ISSN
2235-2988
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Adaptation, PhysiologicalAnimalsBacterial ProteinsDNA, BacterialEpithelial CellsEvolution, MolecularGene Expression Regulation, BacterialGene Transfer, HorizontalGenome, BacterialGenomic IslandsHost-Pathogen InteractionsHumansMembrane ProteinsSalmonella InfectionsSalmonella typhimuriumTranscription FactorsVirulenceVirulence Factors