A New Wrinkle in Biosensors: Wrinkled electrodes could be a breakthrough for lab-on-a-chip devices

Biosensors are analytical devices that sense specific, biologically relevant analytes (such as proteins, nucleic acids, metabolites, polysaccharides, and lipids) using a sensing element and a transducer. Lab-on-a-chip (LOC ) biosensing systems combine several laboratory functions on a single miniaturized chip to identify specific biomarkers for health and environmental monitoring as well as disease management. This allows analytical tests to be carried out on smaller-volume samples, using less volume of expensive reagents and without highly trained technicians or expensive laboratory infrastructure, thereby reducing the costs and time associated with conventional testing.