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The Mortality and Myocardial Effects of...
Journal article

The Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis

Abstract

BACKGROUND: Antidepressants (ADs) are commonly prescribed medications, but their long-term health effects are debated. ADs disrupt multiple adaptive processes regulated by evolutionarily ancient biochemicals, potentially increasing mortality. However, many ADs also have anticlotting properties that can be efficacious in treating cardiovascular disease. We conducted a meta-analysis assessing the effects of ADs on all-cause mortality and …

Authors

Maslej MM; Bolker BM; Russell MJ; Eaton K; Durisko Z; Hollon SD; Swanson GM; Thomson JA; Mulsant BH; Andrews PW

Journal

Psychotherapy and Psychosomatics, Vol. 86, No. 5, pp. 268–282

Publisher

Karger Publishers

Publication Date

2017

DOI

10.1159/000477940

ISSN

0033-3190