Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold Academic Article uri icon

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abstract

  • A series of amide and urea analogues based on the thiaplakortone A natural product scaffold were synthesised and screened forin vitroantimalarial activity.

authors

  • Schwartz, Brett D
  • Skinner-Adams, Tina S
  • Andrews, Katherine T
  • Coster, Mark J
  • Edstein, Michael D
  • MacKenzie, Donna
  • Charman, Susan A
  • Koltun, Maria
  • Blundell, Scott
  • Campbell, Anna
  • Pouwer, Rebecca H
  • Quinn, Ronald J
  • Beattie, Karen
  • Healy, Peter C
  • Davis, Rohan A

publication date

  • February 7, 2015

has subject area